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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '018db0be3a7d29d71b2f47aebf592f17eb5decdfc630fc1a34010643d7c38946' 
  AND token = 'GuPQ23mM/qTfTITunB61hDZ2KbT++1JT5caswi55tOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}