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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '965a7cf5abb3bbf153700421c9102eaa7a6c3a51297cbe1a147da778d62a4337' 
  AND token = '+JM+y9IFKMYPtTjN5qr7Fi/DnIzFQPLO+AiJ8vfPLMc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}