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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2253d110f8f6544feb020e3f052ac5789b43026e5b002c487e4cf8f8efacac6' 
  AND token = 'Bvzw3fKayR9jq8M2hiAp1wF3m2djdntnON4l4sQan7U=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}