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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18f48aa949c0f10b1ba9e6982f8558a8317802f8afe29d69df74533b68dabd59' 
  AND token = 'LRNQHDSVov2uDUmcAO9OC2zJL8utamx2i5Dl3fu0i8g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}