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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a6014c82c3b4e1e18fab578b0177a3117180f4e32a5b82b07a5b7564950ba105' 
  AND token = 'PekPhoTHcSsQkH50pUtmzx4XqBgd/mImLoa20ELeHWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}