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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e782b86539804cdad112cb8af0ff4cb984bd15234c793970733aef7ae18720b1' 
  AND token = '/zlYzhrbtzjIzmRWrx2gs6TdzI5zzRX8lBEdGmqmhIM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}