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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e9e27dda2ead5acea3d743d457104361982286c63ec2ba89e80312a80492fd71' 
  AND token = 'KP4NthzVcR4UICnFW2o4HYR0oU5iTTh/QQVNtY+VA+s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}