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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '142a24c6dcaf49d54b1cdd14bf3b50dcbd7019a6eb11d3f3fcbe65303d06d351' 
  AND token = 'rueHB7tyiXCN8ya6YEB6W/eC2nwJJ80OhEAxEMZT0k4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00051

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}