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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95d56ef39b944b5aadb853b8c6f27d229af3d913bb4b7328a503ae806a729dfd' 
  AND token = 'AfYy2wqVX5/6TL/4BhPY30MKnwVU8y28FSCOEtB3I28=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}