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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f165809f256060cffa64f5a69cf903a71c4a5e0d949de5ba5158439ad13eaed' 
  AND token = 'pS2xRKjTxaQZLh89jkwXVKe4Goy0uzc9qvd+nzCjeSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}