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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '536f057a28bc63ee22ab93933d0e7edba20954fe05c8df3a990403302527280d' 
  AND token = 'x26MMEME/aTH+Jo3kLmcCeVoZKlUPgfHqJhVD9Vzhf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}