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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0e2d0c2f8389584601a4568ba23932a5b7765f7a304efa8281e853684495fc2' 
  AND token = 'CxweYupD67EXfEnM8UTtoi9jTs56sv6w65ZAt1eY6DE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}