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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1de39302d9cd8488974060e91f6d1b7b9fdc803c81ef234c4485cbea2b29e381' 
  AND token = '43i8k8VNEPPbFbbpOk3SCluaReVrbuA0IkEqIFZLrlw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}