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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4017bf3496c0f4449be6e1b659f2052f1590c68ad2124e21549ac6444bae084' 
  AND token = 'p1CHQwFd7d09VAVqaCEHBeHLHgfxnGDKWDveKrI4rYo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}