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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0e5b02e2ca3eafe29299519c55e87280baf6242ef242640806f339d5cddd0c0' 
  AND token = 'T2yIzxWJG4Y0bA+PdA9UevEg1TLGVF5iKOC+8aI2qdM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}