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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4a9ea3fb36ef0eb0d82b7cbef19cfba9203b878ed111d41c65763316da0da7a4' 
  AND token = 'MbjqNy0qD49fWAJHzB6lIlC5OpTrnjBo7Nx4rSmx0bU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}