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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6583073b7b9b03fcb166c8acb10f51f53643a781b821ed9c6052e6f4fac0699' 
  AND token = '+n8rkdMDZiK2jJad66fsZT+6VDbvHrr4dwIasox+f+0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}