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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3add4c3e42ae521e96bf38bae9d620452e4d94e1079d5f51c7cba2254e038e51' 
  AND token = 'iFoMbDL9lVg2EmS11VbpcJkHOcx1sPzCg5zVseYmVBk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}