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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '46b85e3dfafd1d6e08967a27b68a810b237cc44553e06596469b6968719a624c' 
  AND token = 'HOk+CjNTRnZbg0PUrvBPfC/toSbM4o6FhsEhXvfXar0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}