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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52c6c77f3e44aa50798d9730925dda7b2956516ce3c68fa0aba0f21c05718451' 
  AND token = 'ATznX3sm34w5VKH3z8c3U5t+q0RBgPIplyMd7xK/nWc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}