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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4399d46a14239bee27e5b3951ce2b65f0c668aed8946f72c4c1075e9a3239c10' 
  AND token = 'MA7hTQHOntVWXDq2bm6zSduwOHPm2/raEUG1QC7409A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}