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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eec4eef2e9ada7c4ec981c9a63b14f41826d8e48ccfd486afe19377fd1742a48' 
  AND token = 'jOMn8Lt4ENo2ywc0GkCEopoewwAGiv7zK+buMfIE8ws=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}