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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2d17b14649292b376d615bf7b183e0c8a62f6d2db9efcc36978fee799a8227bc' 
  AND token = 'kY+rEO7OdwK5j1vWZ5cP6e2gso6IAPriugBJlItdBMo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}