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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eed63639479223da599d4343d2b7217f4074081f5c3cceee3f0230d08d1f8448' 
  AND token = '1x4iZgYtKkIOesU20OoECGdA69HgGmoNtNiob9Noo2I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}