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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b7b435a4ca8dca28fb14d763548e9efdb7846085d0a9082109d00dc41f60d91' 
  AND token = 'FlE8lqR+LWiQD0XqO4wEjWhOMxAz3rTcAnoW/C6DbxU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}