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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f5dee988e9a6f9d977c4abc7d00767d1ca6ef5e8e42b79d3038438d585c5479' 
  AND token = 'KTFhLufkvOSdby/i8he7nnveVK6e9LiQ5vc7UiA1NRg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}