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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2886dcf24486221ff4cfd9c5e3afa35401d40dd5058a092e9f1efae17c5a655d' 
  AND token = 'dIe95HT8zHS9epgKh3vsZ4XxJVoOIqaYItZqNF5IjEc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}