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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5472a4fb4566e02911a9cad71e8b7f4ad62422c807af65fa5ddf00ef8f7f21a4' 
  AND token = 'p2Y+QACD8zFSVgIXgy+4oOxSwg0dHeIX9WN+BlAKP5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}