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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7f512e7f562743c634cc2d520df2b0fd0a24e61d1a08da4a4074dce724dbcddd' 
  AND token = 'd2TbeIeK6SEWFqE7WXpQNDKx1Ug9UwVRjEQshRzkflU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}