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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70af1db2029769c0aea8ff1ab38db36a9ad3373020e44912a9f3b9607822f292' 
  AND token = '6cIQ4/grizwVPIKAVdB7nAsT1CpC4G+bzjJKqk2zcNg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}