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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25d37b77a6c70ea41fbfd98fe4ae0fd67b3b7fa0dc6b8de37a236ee8e5e4296' 
  AND token = 'zBwiYfCmQFnMy3U0+TryEWzXOjN3UkWpUje7dId92A4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}