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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c1162a3b9d1a26d82cadb99c37238f94698e71d96bd7cb2989ba5eb7dedb253' 
  AND token = 'O+lI/OQ26Nw+snK+LJ7I3pTalwCE11ZV7lmUFgpL2wM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}