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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2457a1a99c405fb2a004fd337b6717cc06a0617570a409402855d909b3be8588' 
  AND token = 'X5lYUFsjJjKu4qI5UP/+oQzUSF5nynTanrmmS6l8SW8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}