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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '782d53f5d8bb89df948843ff2ab67487537542fc655ed4d58f88fff56f27c2c1' 
  AND token = 'ehNDuNTjc1Pu3kPM7ntLCqJHI3dGMa+AOmiudN/BazI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}