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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b2f7851de75b3862d822c262d3cd6b3eb1016200f49fdd224af0c5f84c10fbc' 
  AND token = 'iNBWu896b50rBnBEo/EMz/ag+2zDyyurC/FfhkKBxWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}