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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e175d212281a54c7998b8a3736080236260b3fdaff4b4a967c7717a0bc975100' 
  AND token = 'Ql4/33aIlW35bGH2VhrS3uw3RFrGMyM8rU7m9GfWr5Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}