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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422a336b2306944958e6a9727d994b509fd2f92c249e8f232478b6324e4f4d76' 
  AND token = 'jbM0wLBxQgXrjVFDznmm/0isl9gUAi79pUDDlBiY0Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}