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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'da43cd24d05e3105ceea29a65bd563c40b3113e1404c4203ef0161c27d0fffe1' 
  AND token = 'Dtwy31lHasKnMAJvrIt9C894FfZWuzdtR6ZOtlPkeyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}