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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '728edb62eecafdd1ca03e8768866904990d8708b86057fd0e9f16f025b8822b5' 
  AND token = 'yQ0uWzHqR+zq0+RCF8hEYl5gUHUKYtmVXQ63t279y7I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}