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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '006b4d0f0d5ed97a6765b982560f1a875041b138eee8fd01be0ca9577bbfa743' 
  AND token = '/hutuYErGus0GDWYa4iPZaEEIy+pnESHgoP+kgA2U/c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}