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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aa99a3f8c25ce72505a61464a292a6114346d5a8e981be1597032e98a142755' 
  AND token = 'M+RQLs1Dcv5AU3yDoWuwhB0yt76XbIS/m1YZhb7jm5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}