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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '925fcac76eb7a9c93b237cd5c753d43bbb109e5a067e1bf0d25ab8ff6c4a3edf' 
  AND token = 'KSy4D9gon+wjTYXZITZbuPWDmit5JSZTs1R+Zm3hcRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}