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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51091d97b18d735227b4e15c54d9deae340801f4b5f25032d2a952dbdd0cdaf0' 
  AND token = 'LwEMY4X+Q0d1mIW4KnhPQw+4iEHOIbmE7af6QIV1E9s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}