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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '86418c98a8f4857e1514e541b52ebfbb7d527309f6c0e7eaf02414f30b79e4b3' 
  AND token = 'j04TPbyJ8Mw+LCMJZ18hCfFRAZIYeQB/JDW6agcA8yM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}