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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5624838417a43579e4bf5cd07c9afb8f74d3a39791e4f875d07007dd0a0caa41' 
  AND token = '9TEqCzsIEgRSroKi7nfq+JNBVE8e2OGDApUskDIKTj8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}