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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2428db9b0a5b1568cf95a4164607bc276dd20e1ca09dcb96b05d85c944b128a6' 
  AND token = 'N4vJxIg0+ZB7O8TvfGsxy4wD7oaTtjzQS5le2kWq0Vk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}