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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eee2c65a6a2214cf46542c4184fcaaf4381e35f1eab1830fa577208eaae325e1' 
  AND token = 'e86stiPufTftDU2hWwcSMEsQQzwQSjLsck2sv/C8xXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}