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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c5ed98d011d327a007c5a1587c27cdcfacc60aa0d2e9d621166fdc58d33a57' 
  AND token = 'xV8zp9GyXcbub+8kiOfrJs/m+6N+0yzrOBygU0EKCvE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}