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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f29418137f2203716bc5aebb63eaac19abb48e69bd436d55741bd686a423c6d6' 
  AND token = 'e9GD1jXg+bnGy9su0br7G3NDiy2xaJ9svhB10QtqytA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}