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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8e9125f6dad487ab80f0978c0a7095ab3607ebf4c380a570ec6a63796f2c59e' 
  AND token = 'L21H1bzIayYHj7UBinuzAZGj23TcAuyQRegD1yu0Cfo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}